Campfield Lab

The Campfield Lab studies inflammation and immunity in the lung, partly focused on the role of follistatin-like protein 1 (FSTL-1). Lung infection is the leading cause of childhood mortality worldwide, and new therapies are essential to improving outcomes. We have been focused on host defense mechanisms mediating protection against infection. We had identified that FSTL-1 is a novel gene highly expressed in the lung and important for inflammatory responses and tissue repair; however, the role of FSTL-1 in lung immunity is unknown. The main thrust of our work employs several in vivo and in vitro models of acute inflammation to evaluate mechanisms by which innate immune factors interact with adaptive immune responses in the lung. In turn, the overarching goal lies in understanding how innate immune responses in the lung yield protective responses against infection.

Opportunities

We welcome the opportunity to develop our research program through the addition of talented students and trainees.

If you are interested in becoming a contributing team member, please contact us.

Affiliated Faculty and Staff

• Brian T. Campfield, MD - Principal Investigator
• Matthew A. Henkel, MS - Lab Manager, Lead Technician
• Jessica E. McCreary-Partyka - Lab Technician
• Justin Dutta - Graduate Student
• Andrew Tout - Medical Student