Kidney Workshop (SRIP-Kid)

The mission of the Division of Nephrology is to provide excellence in patient care, training and research for children and young adults with kidney disease.

Our faculty consists of seven pediatric nephrologists, one PhD investigator and three advanced practice provider.

The division has robust external funding for research, including six faculty who are supported by the National Institutes of Health (NIH). The division is a leading recruitment site for the NIH funded CureGN program. The division has active research projects in association with the Pediatric Nephrology Research Consortium. Our division co-hosts the annual Acute Kidney Injury Symposia along with other University of Pittsburgh and UPMC nephrologists and critical care physicians that feature speakers and participants from across the world.   

We are a member of the national Improving Renal Outcomes Collaborative, an organization devoted to eliminating the survival disparity between children with kidney diseases and the general population, and Standardizing Care to Improve Outcomes in Pediatric Endstage Kidney Disease (SCOPE) collaborative, which has the goal to prevent infections in children and adolescents on peritoneal dialysis and hemodialysis and spread effective interventions across pediatric care settings.  

Connect with us on LinkedIn.

The Kidney Workshop internship is under the direction of Jacqueline Ho, MD, and Manisha Jhamb, MD, MPH. 

Program Curriculum Coordinator: Dr. Michelle Manni, PhD.

Program Administrator: Ms. Kathryn Critchlow and Ms. May Hurtado.

Pediatrics and Developmental Focus - Established Mentors:
Dr. Rannar Airik
Dr. Jacqueline Ho
Dr. Alejandro Hoberman
Dr. Neil Hukriede
Dr. Eric Lagasse
Dr. Nader Shaikh

Pediatrics and Developmental Focus - Junior Mentors:
Dr. Takuto Chiba
Dr. Catherine Forster
Dr. Aidan Porter

Adult Nephrology (Renal Electrolyte Division) - Established Mentors:
Dr. Mohammad Al-bataineh
Dr. Gerard Apodaca
Dr. Lori Birder
Dr. Partha Biswas
Dr. Jeffrey Brodsky
Dr. Michael Butterworth
Dr. Marcelo Carattino
Dr. Edwin Jackson
Dr. Manisha Jhamb
Dr. Anthony Kanai
Dr. Ossama Kashlan
Dr. Thomas Kleyman
Dr. Fadi Lakkis
Dr. Paul Palevsky
Dr. Parmjeet Randhawa
Dr. Evan Ray
Dr. Arohan Subramanya
Dr. Roderick Tan
Dr. Angus Thomson
Dr. Steven Weisbord
Dr. Ora Weisz

Adult Nephrology (Renal Electrolyte Division) - Junior Mentors:
Dr. Catherine Baty
Dr. Cary Boyd-Shiwarski
Dr. Shujie Shi

Critical Care Nephrology - Established Mentors:
Dr. Hernando Gomez
Dr. Raghavan Murugan

Critical Care Nephrology - Junior Mentors:
Dr. Dana Fuhrman

Students accepted into the Kidney Workshop must complete eRA Commons registration and enrollment, and the Kidney Workshop curriculum.  

This program is supported by the National Institute of Diabetes, digestive and kidney diseases via an R25 grant (DK119180). 

Publications by Summer Students:

1. Airik, M., H. Arbore, E. Childs, A. B. Huynh, Y. L. Phua, C. W. Chen, K. Aird, S. Bharathi, B. Zhang, P. Conlon, S. Kmoch, K. Kidd, A. J. Bleyer, J. Vockley, E. Goetzman, P. Wipf and R. Airik (2023). "Mitochondrial ROS Triggers KIN Pathogenesis in FAN1-Deficient Kidneys." Antioxidants (Basel) 12(4).

2. Al-Bataineh, M. M., C. L. Kinlough, A. Marciszyn, T. Lam, L. Ye, K. Kidd, J. C. Maggiore, P. A. Poland, S. Kmoch, A. Bleyer, D. J. Bain, N. Montalbetti, T. R. Kleyman, R. P. Hughey and E. C. Ray (2023). "Influence of glycoprotein MUC1 on trafficking of the Ca(2+)-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis." J Biol Chem 299(3): 102925.

3. Boyd-Shiwarski, C. R., D. J. Shiwarski, S. E. Griffiths, R. T. Beacham, L. Norrell, D. E. Morrison, J. Wang, J. Mann, W. Tennant, E. N. Anderson, J. Franks, M. Calderon, K. A. Connolly, M. U. Cheema, C. J. Weaver, L. J. Nkashama, C. C. Weckerly, K. E. Querry, U. B. Pandey, C. J. Donnelly, D. Sun, A. R. Rodan and A. R. Subramanya (2022). "WNK kinases sense molecular crowding and rescue cell volume via phase separation." Cell 185(24): 4488-4506 e4420.

4. Cerqueira, D. M., M. Tayeb and J. Ho (2022). "MicroRNAs in kidney development and disease." JCI Insight 7(9).

5. Costa, R. M., D. M. Cerqueira, L. Francis, A. Bruder-Nascimento, J. V. Alves, S. Sims-Lucas, J. Ho and T. Bruder-Nascimento (2024). "In utero exposure to maternal diabetes exacerbates dietary sodium intake-induced endothelial dysfunction by activating cyclooxygenase 2-derived prostanoids." Am J Physiol Endocrinol Metab 326(5): E555-E566.

6. Lackner, E. M., I. A. Cowan, K. R. Long, O. A. Weisz and K. E. Shipman (2024). "Fluid Shear Stress-Induced Changes in Megalin Trafficking Enhance Endocytic Capacity in Proximal Tubule Cells." bioRxiv.

7. Lackner, E. M., I. A. Cowan, K. R. Long, O. A. Weisz and K. E. Shipman (2024). "Fluid shear stress-induced changes in megalin trafficking enhance endocytic capacity in proximal tubule cells." Front Physiol 15: 1404248.

8. Narla, S. T., J. L. Duara, D. S. Bushnell, M. Nouraie, J. Holden, K. Pfister, P. C. Lucas, S. Sims-Lucas and C. M. Bates (2022). "Role of ERK signaling in bladder urothelium in response to cyclophosphamide injury." Physiol Rep 10(14).

9. Narla, S. T., L. Rice, D. Ostrov, S. G. Swarts, D. W. Siemann, D. S. Bushnell, J. G. Holden, J. L. Duara and C. M. Bates (2022). "FGF7 peptide (FGF7p) mimetic mitigates bladder urothelial injury from cyclophosphamide." Physiol Rep 10(7): e15241.

10. Pfister, K., V. Young, B. Frankel, A. Silva Barbosa, J. Burton, J. Bons, B. Zhang, T. Chiba, R. Uhlean, E. Goetzman, B. Schilling and S. Sims-Lucas (2024). "Succinylation of Park7 activates a protective metabolic response to acute kidney injury." Am J Physiol Renal Physiol 327(1): F128-F136.

11. Shipman, K. E., C. J. Baty, K. R. Long, Y. Rbaibi, I. A. Cowan, M. Gerges, A. L. Marciszyn, O. B. Kashlan, R. J. Tan, A. Edwards and O. A. Weisz (2023). "Impaired Endosome Maturation Mediates Tubular Proteinuria in Dent Disease Cell Culture and Mouse Models." J Am Soc Nephrol 34(4): 619-640.

12. Shipman, K. E., K. R. Long, I. A. Cowan, Y. Rbaibi, C. J. Baty and O. A. Weisz (2022). "An Adaptable Physiological Model of Endocytic Megalin Trafficking in Opossum Kidney Cells and Mouse Kidney Proximal Tubule." Function (Oxf) 3(6): zqac046.

13. Silva Barbosa, A. C., K. E. Pfister, T. Chiba, J. Bons, J. P. Rose, J. B. Burton, C. D. King, A. O'Broin, V. Young, B. Zhang, B. Sivakama, A. V. Schmidt, R. Uhlean, A. Oda, B. Schilling, E. S. Goetzman and S. Sims-Lucas (2024). "Dicarboxylic Acid Dietary Supplementation Protects against AKI." J Am Soc Nephrol 35(2): 135-148.

14. Staniorski, C. J., A. Paul and R. Chaudhry (2024). "Prospective assessment of entrance skin dose and targets for radiation reduction during abdominal plain films in pediatric urology patients." J Pediatr Urol 20(5): 793-798.

15. Wang, X. P., S. M. Mutchler, R. Carrisoza-Gaytan, M. Al-Bataineh, C. J. Baty, A. Vandevender, P. Srinivasan, R. J. Tan, M. J. Jurczak, L. M. Satlin and O. B. Kashlan (2023). "Mineralocorticoid receptor-independent activation of ENaC in bile duct ligated mice." bioRxiv.

16. Wang, X. P., S. M. Mutchler, R. Carrisoza-Gaytan, A. J. Nickerson, C. J. Baty, M. Al-Bataineh, A. Vandevender, T. Morimoto, P. Srinivasan, R. J. Tan, M. J. Jurczak, L. M. Satlin and O. B. Kashlan (2024). "Epithelial Na + Channel Activation after Bile Duct Ligation with Mineralocorticoid Receptor Blockade." J Am Soc Nephrol 35(11): 1466-1477.

17. Wang, X. P., P. Srinivasan, M. El Hamdaoui, B. M. Blobner, R. Grytz and O. B. Kashlan (2024). "Varying Selection Pressure for a Na+ Sensing Site in Epithelial Na+ Channel Subunits Reflect Divergent Roles in Na+ Homeostasis." Mol Biol Evol 41(8).

18. Whelan, S. C. M., S. M. Mutchler, A. Han, C. Priestley, L. M. Satlin, T. R. Kleyman and S. Shi (2024). "Kcnma1 alternative splicing in mouse kidney: regulation during development and by dietary K(+) intake." Am J Physiol Renal Physiol 327(1): F49-F60.