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In 2007, the Richard King Mellon Foundation made a generous financial contribution to create the Richard King Mellon Institute for Pediatric Research (RKMI), some of which was spent constructing the Rangos Research Center. Since that time, additional financial support was obtained from a generous gift from the Tull Family Foundation to support pediatric research initiatives within the RKMI.
The RKMI began as a small group of investigators (termed “Mellon Scholars”) housed in the Rangos Research Center and functioned as a small, independent division within the Department of Pediatrics. In 2018, the RKMI expanded its mission with the objective to support talented scientists in the early stages of their careers performing cutting-edge pediatric research.
The overarching goal of the RKMI is to become the cornerstone of basic and clinical research within UPMC Children’s Hospital of Pittsburgh, encompassing a wide reach to facilitate synergy, communication, and mentorship across all research disciplines under the UPMC Children's umbrella, regardless of department or division. We believe that the diversity surrounding the professional experiences and scientific interests of the Mellon Scholars will accelerate collaboration across divisions and departments at UPMC Children's for the continual pursuit of excellence in pediatric healthcare.
Leadership
George K. Gittes, MD - Director
Timothy W. Hand, PhD - Associate Director
Kristin N. Ray, MD. MS. FAAP - Associate Director
John F. Alcorn - Associate Director
Current Mellon Scholars
Rannar Airik, PhD – New strategies to treat kidney failure
Kelly M. Baily, MD, PhD – The Ewing sarcoma microenvironment and immune responses to pediatric sarcomas
Erica Braverman, MD - Creating better chimeric antigen receptor (CAR) T cells for pediatric sarcomas
Daniela Brissett, MD - Developing innovative, community-engaged tools to measure and address adultification and its impact on the health and identity of marginalized youth
Brian Campfield, MD – Fending off foreign attacks on the lung
Shaun Carlson, PhD - The identification of therapeutic approaches to promote recovery after brain injury.
Takuto Chiba, PhD - Microvascular Protection Against Kidney Injury
Jessica Daley, MD - Identifying and reversing mechanisms driving immunosuppression in Ewing Sarcoma
Will DePas, PhD – Biogeography of bacterial infections
Megan Culler Freeman, MD, PhD - Understanding how viruses cause paralysis
Catherine Forster, MD, MS, FAAP – Urobiome in UTIs
Taylor Eddens, MD, PhD - Examining early life immune responses to viral infections and the connection to asthma development
Kristina Gaietto, MD - Pediatric asthma research with a focus on endotypes, omics, stress-related impacts, COVID-19 outcomes, and pulmonary function
Lina Ghaloul Gonzalez, MD – Plain people (Amish/Mennonites) translational medicine
Radha Gopal, PhD - Cardiovascular diseases associated with viral infection
Katherine Guyon-Harris, PhD - Interventions to support positive parent-child relationships across the perinatal period
Jessica Jarvis, PhD, MT-BC - Improving the efficacy and equity of pediatric rehabilitation services for children with chronic and serious illnesses
Heather Joseph, DO - Early signals of inattention among infants and toddlers at familial risk for ADHD and behavioral interventions for parents and young children with ADHD
Melissa Kane, PhD – Viruses and the immune system
Laura Kirkpatrick, MD - Reproductive health and epilepsy
Christine March, MD, MS - Optimizing health care delivery and outcomes for youth with diabetes
Lisa Mauer, MD, PhD - The role of GRK2 in inhibition of the MALT1 proto-oncoprotein in lymphomagenesis
Cody Nesvick, MD - Understanding and targeting the epigenetic mechanisms of atypical teratoid rhabdoid tumors (ATRT) in young children
Carolina Pinzon - Molecular mechanisms of foregut congenital anomalies (EA/TEF and CDH)
Catherine Poholek, MD, PhD - Investigating the underlying etiologies of pediatric autoimmune disease to improve treatment options and the role of lipid metabolism and a cholesterol-binding protein called apolipoprotein E in lymph node stromal cells during the immune response
Aiden Porter, MD - Exploring kidney cell stress responses to uncover drug targets for treating kidney injury
Vikram Raghu, MD, MS - Cost-effectiveness and decision-making in pediatric intestinal failure and transplantation
Jacquelin Rankine, MD, PhD - Optimizing school health services to improve health and educational outcomes
Glenn Rapinski, MD, PhD - Understanding interactions between the bacteria Pseudomonas aeruginosa and the patient that lead to ventilator-associated infections, particularly in children who have tracheostomies
Anne-Marie Rick, MD, MPH, PhD - Protection against newborn infections through maternal immunity
Franziska Rosser, MD, MPH, FAAP – Epidemiological effects of outdoor air pollution on children with asthma
Jenny Ruiz, MD, MSCE - Language discordant communication research in pediatric oncology
Anita Pradeep Saraf, MD, PhD – Developing a better understanding the role of genetic mutations, chronic inflammation and mechanical strain on cardiomyocytes
Kelsey Schweiberger, MD, MS - The appropriate application of technology to improve child health outcomes, and the role that technology plays in physician-patient communication
Laurie Silva, PhD – Viral and host determinants of virus replication and pathogenesis
Emir Tas, MD - Sex-specific mechanisms of early cardiometabolic risk in youth with type 1 diabetes
Mary Ellen Vajravelu, MD, MSHP - Improving outcomes and achieving health equity for youth with type 2 diabetes
Anna Wang-Erickson, PhD - Infectious disease epidemiology, global health, bacterial genetics, vaccines and phage therapy development
Tyia Wilson, PhD - Promoting resilience and reducing substance use in youth under chronic stress
Yijen Wu, PhD - MuSIC 4 MIND - Multi-Systems Imaging Characterization for Mitochondrial Involvement in Neurological Disease
Xiangwei Xiao, MD, PhD – Insulin cell function and preservation
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