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Nilay Mitash, PhD
- Postdoctoral Associate
Nilay Mitash, PhD is a postdoctoral fellow who graduated from the Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. Nilay has been studying the role of microRNAs in regulating channels and transporters in polarized human airway epithelial cells.
Education & Training
- BSc, Zoology, Babasaheb Bhimrao Ambedkar Bihar University, 2004
- MSc, Biotechnology, Allahabad Agricultural Institute-Deemed University, 2008
- PhD, Department of Urology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, 2016
Selected Publications
Mitash N, Agnihotri S, Tiwari S, Agrawal V, Mandhani A. MicroRNA-21 could be a molecular marker to predict the recurrence of nonmuscle invasive bladder cancer. Indian J Urol. 2017 Oct-Dec;33(4):283-290. doi: 10.4103/iju.IJU_4_17. PubMed PMID: 29021651; PubMed Central PMCID: PMC5635668. {Impact Factor (I.F.) =0.61}
Mitash N, Tiwari S, Agnihotri S, Mandhani A. Bladder cancer: Micro RNAs as biomolecules for prognostication and surveillance. Indian J Urol. 2017 Apr-Jun;33(2):127-133. doi: 10.4103/0970-1591.203412. Review. PubMed PMID: 28469300; PubMed Central PMCID: PMC5396400. (I.F.=0.61)
Sureka SK, Maheshwari R, Agnihotri S, Mitash N, Ahmad S, Mandhani A. Predictors for progression of metastatic prostate cancer to castration-resistant prostate cancer in Indians. Indian J Med Res. 2016 May;143 (Supplement):S68-S73. doi: 10.4103/0971-5916.191783. PubMed PMID: 27748280; PubMed Central PMCID: PMC5080931. (I.F.=2.06)
Mitash N, Agnihotri S, Mittal B, Tiwari S, Mandhani A. Molecular cystoscopy: Micro-RNAs could be a marker for identifying genotypic changes for transitional cell carcinoma of the urinary bladder. Indian J Urol. 2016 Apr-Jun;32(2):149-53. doi: 10.4103/0970-1591.174775. PubMed PMID: 27127359; PubMed Central PMCID: PMC4831505. (I.F.=0.9)
Bansal N, Gupta A, Mitash N, Shakya PS, Mandhani A, Mahdi AA, Sankhwar SN, Mandal SK. Low- and high-grade bladder cancer determination via human serum-based metabolomics approach. J Proteome Res. 2013 Dec 6;12(12):5839-50. doi: 10.1021/pr400859w. Epub 2013 Nov 18. PubMed PMID: 24219689. (I.F.=5.0)
Mitash N*, Mu F., Donovan J.E., Myerburg M.M., Ranganathan S., Greene C.M., Swiatecka-Urban A*. Transforming Growth Factor-β1 Selectively Recruits microRNAs to the RNA-Induced Silencing Complex and Degrades CFTR mRNA under Permissive Conditions in Human Bronchial Epithelial Cells. Int. J. Mol. Sci. 2019, 20, 4933. *Corresponding Authors (I.F.=4.2)
Gupta A, Bansal N, Mitash N, Kumar D, Kumar M, Sankhwar SN, Mandhani A, Singh UP. NMR-derived targeted serum metabolic biomarkers appraisal of bladdercancer: A pre- and post-operative evaluation. Journal of Pharmaceutical and Biomedical Analysis. Feb 2020 (I.F.=2.98)
De Santi C, Fernández EF, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall D, Cutrona MB, Simpson JC, Harvey BJ, Linnane B, McNally P, Cryan SA, MacLoughlin R, Swiatecka-Urban A, Greene CM. Precise targeting of specific miR-145-5p or miR-223-3p binding sites restores CFTR activity and enhances CFTR modulator action in CF bronchial epithelial cells. Molecular Therapy Feb 2020 (In-Press).
Cruz DF, Mitash N, Farinha CM, Swiatecka-Urban A. TGF-β1 augments the apical membrane abundance of Lemur tyrosine kinase 2 to inhibit CFTR-mediated chloride transport in human bronchial epithelia. Frontiers in Cell and Developmental. Feb 2020 (In-Press)
Mitash N*, Donovan J.E., Swiatecka-Urban A*. The role of microRNAs in the airway surface liquid homeostasis and host defense in the human airway. (Invited Review Manuscript submitted in IJMS). *Corresponding Authors
Academic and Research Interests
- Micro RNA
- Non-coding RNA
- Cystic Fibrosis
- Cancer Pulmonary Disease
- miRNA based signaling mechanism